(A) The cumulative data of IL-10 level of Treg-of-B cells or T-of-B cells with transwell, [To(B)] during the culture period from 3 individual experiments. (B) Suppression assay. (C) Representative flow plots of markers on ToB3 and To(B)3 cells from 2 individual experiments. (D) The cumulative data of frequency of marker-expressing populations in ToB1, ToB3, and To(B)3 cells from 2–3 individual experiments. Data shown were the representative of at least 3 individual experiments.