Table 4: Adjusted scores during Japanese cedar/cypress pollen season (entire pollen season) and Japanese cedar pollen (JCP) season.

From: Safety and efficacy of short-term oral immunotherapy with Cry j 1-galactomannan conjugate for Japanese cedar pollinosis: a randomized controlled trial

 Active groupPlacebo groupDifferencep value95% CI of the difference
(n = 26)(n = 28)
Entire pollen season
Symptom-medication score
 Mean (SE)1.44 (0.3)2.01 (0.3)−0.560.085−1.21 to 0.08
 Median (Q1-Q3)1.52 (0.89–2.12)1.91 (1.03–3.01)   
Total Symptom score
 Mean (SE)6.41 (0.8)6.28 (0.7)0.130.891−1.77 to 2.03
 Median (Q1-Q3)5.96 (3.92–8.92)6.04 (3.88–9.00)   
Medication score
Mean (SE)0.41 (0.2)0.96 (0.2)−0.540.040−1.06 to −0.02
 Median (Q1-Q3)0.40 (0.09–0.84)0.55 (0.27–1.54)   
Total nasal score
 Mean (SE)4.69 (0.6)4.40 (0.5)0.280.674−1.07 to 1.64
 Median (Q1-Q3)4.31 (2.92–5.69)4.96 (2.46–6.35)   
Total ocular score
 Mean (SE)1.73(0.3)1.85(0.3)−0.130.703−0.80 to 0.55
 Median (Q1-Q3)1.69(0.85–2.85)1.65(1.00–2.81)   
JCP season
Symptom-medication score
 Mean (SE)1.69 (0.3)2.36 (0.3)−0.660.075−1.40 to 0.07
 Median (Q1-Q3)2.05 (0.99–2.55)2.21 (1.25–3.45)   
Total Symptom score
 Mean (SE)7.25 (1.0)7.13 (0.8)0.120.911−2.02 to 2.25
 Median (Q1-Q3)7.25 (4.63–10.75)7.50 (4.38–10.38)   
Medication score
 Mean (SE)0.51 (0.3)1.16 (0.2)−0.650.033−1.24 to −0.05
 Median (Q1-Q3)0.43 (0.07–1.14)0.79 (0.21–1.73)   
Total nasal score
 Mean (SE)5.24 (0.7)4.74 (0.6)0.50.506−0.99 to 1.99
 Median (Q1-Q3)5.13 (3.50–6.88)5.31 (2.69–7.13)   
Total ocular score
 Mean (SE)2.09(0.3)2.33(0.3)−0.240.538−1.02 to 0.54
 Median (Q1-Q3)2.13(1.13–3.38)2.13(1.44–3.31)   
  1. Maximum symptom-medication score (total symptom score/6 plus medication score) = 13; maximum total symptom score = 24; maximum medication score = 9; maximum total nasal score = 16; and maximum total ocular score = 8.
  2. Scores are shown as the least square (LS) means adjusted by analysis of covariance (ANCOVA) model, with symptom-medication score in the pre-pollen season, and sensitization status of cypress pollen and house dust mite as factors in the analysis. Statistical analysis was performed using ANCOVA.