Figure 4

From: Chlorin e6 mediated photodynamic inactivation for multidrug resistant Pseudomonas aeruginosa keratitis in mice in vivo

Figure 4

Representative corneal manifestations of mice treated by regimen I (chlorin e6 mediated PDI at 24 h post infection), in which PDI was mediated by (A,B,C) 0%, (D,E,F) 0.01%, (G,H,I) 0.05% and (J,K,L) 0.1% chlorin e6 (Ce6). Photos were taken (A,D,G,J) right before infection of P. aeruginosa (hour 0), (B,E,H,K) before PDI (hour 24), and (C,F,I,L) on day 3. (E) A characteristic infiltration ring of P. aeruginosa keratitis (clinical score 3). The corneal suppurative infiltration developed rapidly in all mice, but on day 3, it seemed to be milder in (L) the mouse treated by 0.1% Ce6 mediated PDI (clinical score 3) than the others (clinical score 4).