Table 3: Multivariate-adjusted risk factors associated with CRC.

From: Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study

  Adjusted ORaCI 95%
Genetic Risk ScoreGRS (per allele)1.071.04–1.10
Family history of CRC 2.251.87–2.72
Environmental risk factorsAlcohol1.341.12–1.60
BMI ≥ 30 kg/m21.291.01–1.65
No physical activity1.341.16–1.55
Vegetables ≤ 200 g/day1.361.15–1.58
Red meat > 65 g/day1.291.12–1.49
No NSAID/ASA regular use1.571.33–1.86
ERS (per factor)1.361.27–1.45
  1. CRC: colorectal cancer; GRS: genetic risk score; ERS: environmental risk score; BMI: body mass index; NSAID: nonsteroidal anti-inflammatory drugs; ASA: acetylsalicylic acid.
  2. aAll variables are adjusted by propensity score and all the variables shown in the table.
  3. bThe reference category is 22 risk alleles, the average in the population.