Table 1: Association between the 21 selected previously reported SNPs and risk of CRC in the study population.

From: Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study

SNPChrPositionMapped GeneRisk AlleleRisk Allele FrequencyReported p-valueReported OROR MCC-Spain95% CIp-value
rs107528811183004356KRT18P28 - LAMC1A0.765.0E-061.071.111.01–1.210.04
rs66911701221872104DUSP10 - QRSL1P2T0.311.0E-091.061.090.99–1.200.08
rs109365993169774313MYNNC0.193.0E-081.041.100.98–1.230.11
rs1321311636655123N/AC0.301.0E-101.101.030.93–1.150.54
rs77582296160419220SLC22A3T0.678.0E-091.281.070.96–1.180.21
rs168927668116618444LINC00536 - EIF3HC0.393.0E-181.271.170.98–1.390.08
rs69832678127401060CCAT2 - LOC101930033G0.821.0E-141.271.101.00–1.210.04
rs10795668108659256RNA5SP299 - LINC00709G0.735.0E-151.151.060.95–1.170.30
rs49483171058811675BICC1C0.307.0E-081.101.070.97–1.180.19
rs380284211111300984COLCA2 - COLCA1C0.086.0E-101.111.090.98–1.200.12
rs38249991174634505POLD3G0.134.0E-101.081.091.00–1.200.06
rs108793571272020783TPH2G0.503.0E-061.251.000.91–1.110.94
rs111695521250761880DIP2B - ATF1C0.822.0E-101.091.020.91–1.140.80
rs731543812115453598TBX3 - UBA52P7T0.416.0E-061.111.030.94–1.130.53
rs44442351453944201RPS3AP46 - MIR5580C0.438.0E-101.111.030.94–1.130.51
rs99292181668787043CDH1G0.461.0E-081.101.131.01–1.250.03
rs49398271848927093SMAD7T0.278.0E-281.201.221.11–1.340.03
rs104112101933041394RHPN2C0.315.0E-091.151.010.88–1.160.92
rs49253862062345988LAMA5C0.582.0E-101.081.080.98–1.190.14
rs961253206423634FGFR3P3 - CASC20A0.282.0E-101.121.101.00–1.220.05
rs5934683X9783434GPR143 - SHROOM2C0.577.0E-101.071.040.93–1.170.46
  1. SNPs associated with CRC risk in MCC population with p < 0.05 are highlighted in bold.