Table 1 The most significantly differentially expressed genes in All atherosclerotic plaques versus atherosclerosis free control arteries (LITA), (FC ≥ ± 15 and FDR < 0.05) and the corresponding FC and p-values from comparisons between atherosclerotic plaques from different arterial beds (abdominal aorta, carotid, femoral) compared to LITA.

From: Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques – Tampere Vascular Study

Gene symbol ACCESSION All vs. LITA Aorta vs. LITA Carotid vs. LITA Femoralis vs LITA
FC P-value FC p-value FC p-value FC p-value
SPP1 NM_001040058.1 121.9 1.82*10−13 104.3 2.73*10−8 135.7 1.19*10−15 105.4 3.16*10−14
SPP1 NM_000582.2 109.1 1.82*10−13 90.9 2.73*10−8 113.9 1.19*10−15 99.9 3.16*10−14
MMP12 NM_002426.2 88.9 1.82*10−13 72.4 2.73*10−8 124.9 1.19*10−15 68.3 3.16*10−14
MMP9 NM_004994.2 76.1 1.82*10−13 32.0 2.73*10−8 98.8 1.19*10−15 76.9 3.16*10−14
CIDEC NM_022094.2 −61.2 2.91*10−11 −17.0 2.00*10−3 −90.4 1.19*10−15 −50.1 3.71*10−10
KIAA1881 XM_001130790.1 −60.1 9.97*10−12 −17.7 2.73*10−8 −80.1 1.19*10−15 −50.9 6.60*10−11
LOC642113 XM_936253.1 53.3 5.44*10−12 135.0 2.91*10−8 36.1 8.72*10−12 38.7 3.71*10−10
MMP7 NM_002423.3 52.5 2.21*10−13 17.8 3.93*10−8 91.8 1.19*10−15 36.2 3.16*10−14
LOC647450 XM_936518.1 52.4 5.12*10−12 153.5 2.91*10−8 47.6 8.72*10−12 32.5 2.94*10−10
LOC652493 XM_941953.1 52.1 3.55*10−12 127.7 2.91*10−8 45.2 4.17*10−12 32.1 1.82*10−10
LOC652694 XM_942302.1 47.2 3.14*10−12 129.4 2.14*10−8 46.0 2.48*10−12 22.2 1.43*10−10
MMP12 NM_002426.2 47.1 7.00*10−13 72.4 2.73*10−8 63.2 1.19*10−15 25.5 1.43*10−10
APOD NM_001647.2 −39.7 1.24*10−10 −1.4 3.76*10−2 −68.1 1.19*10−15 −43.9 3.16*10−14
APOC1 NM_001645.3 36.2 2.21*10−13 30.3 9.94*10−11 53.2 2.38*10−15 32.8 6.33*10−14
PLA2G7 NM_005084.2 29.9 2.21*10−13 12.5 5.97*10−10 43.6 1.19*10−15 28.0 3.16*10−14
MMP7 NM_002423.3 28.3 2.21*10−13 17.8 1.99*10−10 54.6 1.19*10−15 21.2 3.16*10−14
KIAA1199 NM_018689.1 25.5 1.82*10−13 31.0 4.97*10−11 26.5 1.19*10−15 19.5 3.16*10−14
CIDEA NM_001279.2 −24.5 6.22*10−11 −17.9 5.42*10−5 −30.4 8.13*10−13 −23.4 4.46*10−8
ADAMDEC1 NM_014479.2 24.2 1.82*10−13 26.1 4.97*10−11 28.5 1.19*10−15 15.0 3.16*10−14
SCARA5 NM_173833.4 −22.8 6.16*10−13 −3.3 1.08*10−6 −27.0 1.19*10−15 −23.8 3.16*10−14
ACP5 NM_001611.2 22.6 4.78*10−13 7.4 3.40*10−8 31.4 1.19*10−15 32.0 3.16*10−14
IGLL1 NM_020070.2 20.0 7.83*10−12 38.1 1.99*10−10 19.2 1.39*10−11 16.0 1.70*10−9
LOC652102 XM_941434.1 19.0 5.23*10−11 58.9 4.97*10−11 16.6 2.53*10−10 11.9 7.40*10−8
APOE NM_000041.2 17.6 7.45*10−13 15.8 1.34*10−7 27.7 2.38*10−15 16.4 3.16*10−14
PLIN NM_002666.3 −17.3 5.87*10−11 −12.9 4.66*10−5 −19.0 1.44*10−12 −18.5 1.70*10−9
ACTA1 NM_001100.3 −16.3 7.40*10−11 −9.3 7.02*10−7 −19.6 2.26*10−14 −9.2 3.86*10−7
RGS1 NM_002922.3 15.8 6.57*10−13 23.9 4.97*10−11 12.0 8.13*10−13 12.6 3.80*10−13
OLR1 NM_002543.3 15.8 3.70*10−13 20.6 5.97*10−10 15.4 5.35*10−14 17.1 1.27*10−13
MYOC NM_000261.1 −15.2 3.05*10−13 −11.1 2.24*10−9 −17.8 1.19*10−15 −10.9 6.33*10−14
  1. aAbbreviations: FC = fold changes (FC); FDR = False discovery rate; LITA = left internal thoracic artery.