Figure 1 : Three different strategies to measure adhesion force using AFM.

From: Investigation of Cell-Substrate Adhesion Properties of Living Chondrocyte by Measuring Adhesive Shear Force and Detachment Using AFM and Inverse FEA

Figure 1

(a) AFM cantilever is approached onto an adhered cell on substrate to measure adhesion force between the cell and tip, (b) Cell attached to the cantilever is brought into contact with another adhered cell (or a surface of interest) to measure adhesion force between two cells (or between cell and a surface of interest), (c) AFM cantilever is used to apply a shear force on the cell until it’s detached to measure adhesion force between the cell and substrate.