Figure 6 : TRB3 overexpression alleviates miR-124 induced TG retention.

From: MicroRNA-124 promotes hepatic triglyceride accumulation through targeting tribbles homolog 3

Figure 6

(A) Western blot analysis of TRB3 and phospho-Akt in the liver of mice infected with Ad-miR-124 or both Ad-miR-124 and Ad-TRB3. (B) Liver TG levels in mice infected with Ad-miR-124 or both Ad-miR-124 and Ad-TRB3 (n = 8–9). (C) Oil Red O staining showing TG accumulation in the liver from mice infected with Ad-miR-124 or both Ad-miR-124 and Ad-TRB3. Original magnification, x200. (D) Serum TG levels in mice infected with Ad-miR-124 or both Ad-miR-124 and Ad-TRB3 (n = 8–9). (E) Relative mRNA expression of lipogenic genes in the liver from mice infected with Ad-miR-124 or both Ad-miR-124 and Ad-TRB3 (n = 8–9). *P < 0.05, **P < 0.01, ***P < 0.001.