Table 4: Purkinje cell activity during electrophysiological recordings before and after phase reversal adaptation in 5 mutant mice.

From: Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments

 SS naïveSS afterModel naïveModel afterCS naïveCS after
GC-ΔKCC2n = 5n = 9runs = 30runs = 30n = 5n = 9
FF (Hz)53.6 ± 10.577.8 ± 7.682.2 ± 0.599.0 ± 0.61.1 ± 0.01.3 ± 0.2
AMP (Hz)12.2 ± 3.219.4 ± 4.020.8 ± 0.731.2 ± 0.81.2 ± 0.41.3 ± 0.3
PHASE265 ± 15244 ± 6171 ± 1166 ± 176 ± 465 ± 7
PC-Δγ2n = 8n = 10runs = 30runs = 30n = 8n = 10
FF (Hz)44.9 ± 3.658.2 ± 3.766.5 ± 0.273.9 ± 0.30.9 ± 0.10.7 ± 0.1
AMP (Hz)5.8 ± 3.420.2 ± 4.54.05 ± 0.311.1 ± 0.51.4 ± 0.10.8 ± 0.2
PHASE243 ± 2244 ± 7128 ± 2.4146 ± 1.083 ± 2387 ± 12
PC-ΔKCC2n = 9n = 12runs = 30runs = 30n = 9n = 12
FF (Hz)60.8 ± 7.461.6 ± 6.366.5 ± 0.273.9 ± 0.31.0 ± 0.10.9 ± 0.1
AMP (Hz)6.4 ± 2.714.5 ± 2.94.1 ± 0.311.1 ± 0.51.1 ± 0.21.1 ± 0.2
PHASE225 ± 14224 ± 19128 ± 2.4146 ± 1.056 ± 872 ± 3
PC-ΔPP2Bn = 9n = 12runs = 30runs = 30n = 9n = 12
FF (Hz)47.4 ± 4.233.9 ± 3.40 ± 00 ± 01.1 ± 0.10.9 ± 0.1
AMP (Hz)8.6 ± 5.015.8 ± 4.29.3 ± 09.3 ± 01.1 ± 0.21.1 ± 0.2
PHASE253 ± 16184 ± 33181 ± 0181 ± 0192 ± 3375 ± 12
PC-ΔCACNA1An = 9 runs = 30runs = 30n = 9 
FF (Hz)60.5 ± 5.2 60.1 ± 060.1 ± 01.0 ± 0.1 
AMP (Hz)8.6 ± 1.6 0.9 ± 00.9 ± 01.3 ± 0.2 
PHASE223 ± 25 181 ± 0181 ± 081 ± 12 
  1. All data are presented as mean ± SEM. Group sizes are denoted by n animals. “Runs” indicate the number of iterations or the model.