Table 3 Systemic insulin resistance and inflammatory markers following conventionalization of germ-free mice by SF and CTL fecal microbiome.

From: Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

  TF-SF (n = 8) TF-CTL (n = 8) Non-TF Germ-Free (n = 4) P-value (TF-SF vs. TF-CTL or Non-TF)
HOMA-IR 6.2 ± 2.5 3.4 ± 1.4 3.4 ± 1.5 <0.01
NGAL (ng/ml) 198.4 ± 46.8 77.6 ± 35.7 64.3 ± 45.1 <0.01
LBP (ng/ml) 112.6 ± 23.8 44.9 ± 22.1 27.9 ± 20.2 <0.01
IL-6 (pg/ml) 35.4 ± 8.4 19.5 ± 7.2 12.6 ± 5.5 <0.05