Figure 7 | Scientific Reports

Figure 7

From: Inter-isoform Hetero-dimerization of Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A9 and 2B7 and Impacts on Glucuronidation Activity

Figure 7

Enzyme kinetic plots (A,C,E,G), V/[S]-V plots (B,F′) and Eadie-Hofstee plots (B″,D,F″,H) of M1 (quercetin-7-glucuronide) formation by UGT1A9*NCFP/2B7*NHA co-expression systems. Glucuronidation rates are mean ± SD of three independent determinations and normalized according to relative expression levels. The respective kinetic constants are presented in Table 4.

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