Figure 10 | Scientific Reports

Figure 10

From: Inter-isoform Hetero-dimerization of Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A9 and 2B7 and Impacts on Glucuronidation Activity

Figure 10

Enzyme kinetic plots (A,C,E,G) and Eadie-Hofstee plots (B,D,F,H) of zidovudine O-glucuronidation by UGT1A9*NCFP/2B7*NHA co-expression systems. Glucuronidation rates are mean ± SD of three independent determinations and normalized according to relative expression levels. The respective kinetic constants are presented in Table 7.

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