(A) Heatmap of the SNP-Freqc (definition in Materials and Methods) on each chromosome for the 83 single-cell samples obtained by the GATK. (B) Heatmap of the SNP-Freqc on each chromosome for the bulk (both cancer and normal) samples obtained by the GATK. The SNP enrichment on chromosomes for each single-cell and bulk (both cancer and normal) sample was shown in the heatmaps. In each heatmap, the columns represented the samples, and the rows corresponded to different chromosomes. The SNP-Freqc on a logarithmic scale (e-based) was encoded by a colored bar. The largest SNP-Freqc values were displayed in red, and the smallest values were displayed in blue. Chromosomes that fell into one cluster (horizontal axis) had a similar SNP-Freqc between the samples. The samples were also clustered (vertical axis) based on the SNP-Freqc value of each sample.