Table 1: Baseline demographic and clinical (A), echocardiographic and biochemical (B) characteristics of patients referred with suspected TB pericarditis.

From: The diagnostic accuracy of pericardial and urinary lipoarabinomannan (LAM) assays in patients with suspected tuberculous pericarditis

 AllDefinite-TBProbable-TBNon-TB
N = 151n = 74n = 50n = 27
A.
Demographics
Age (median, IQR)34 (29–42)33 (27–38)*33 (28–37)*52 (34–60) *p < 0.001
Male (n, %)93 (62)48 (65)32 (64)13 (48)
HIV positive (n, %)¥105 (74)59 (80)*41 (82)*5 (28) *p < 0.001
CD4 count (median, IQR)¥139 (81–249)131 (70–206)*153 (81–271)*301 (229–424) *p = 0.04
ARV therapy (n/N, %)18/98 (18)10/54 (19)7/39 (18)1/5 (20)
Presenting clinical features
NYHA Class I–II (n/N, %)77/134 (58)39/66 (59)*35/47 (75)*3/21 (14) *p < 0.001
NYHA Class III–IV (n/N, %)57/134 (41)27/66 (41)*12/47 (25)*18/21 (86) *p < 0.001
Systolic Blood Pressure (mean, SD) (n = 145)113 (17)113 (17)112 (16)115 (22)
Diastolic Blood Pressure (mean, SD) (n = 145)72 (14)72 (15)72 (13)73 (14)
Heart rate (mean, SD) (n=146)111 (20)114 (22)108 (16)111 (21)
Serum biochemical data
Haemoglobin g/dl (mean, SD)9.6 (2.1)9.4 (2.1)*9.3 (1.7)*10.9 (2.3) *p = 0.004
Creatinine, μmol/l (median, IQR)73 (59–90)72 (58–86)77 (61–92)72 (61–81)
Total WCC × 109/l (median, IQR)6.5 (4.8–9.3)6.5 (4.4–8.2)*5.8 (4.8–7.2)*10.5 (7.1–15.2) *p < 0.001
B.
Echocardiographic features
Size of effusion (mm)(mean, SD) (n = 126)36 (14)36 (14)*38 (13)*29 (14) *p < 0.001
Tamponade (n, %) (n = 141)94 (67)50 (72)32 (64)12 (55)
Routine pericardial fluid analyses
ADA IU/l (median, IQR) (n = 142)51 (34–75)59 (45–86)*51 (34–77)*17 (11–27)* p < 0.001
Total protein g/l (median, IQR) (n = 148)60 (52–68)59 (53–68)63 (56–68)56 (48–62)
Lactate Dehydrogenase (median, IQR) (n = 135)1419 (867–2305)1553 (999–2800)*1093 (725–1613)*884 (442–2305) *p = 0.02
Total PF WCC × 109/l (Median, IQR) (n = 136)2.1 (1.1–3.3)2.0 (1.2–3.0)2.2 (1.2–2.9)3.0 (0.7–8.9)
Lymphocyte predominance (n/N, %)§52/107(49)29/56 (52)*22/34 (65)*1/17 (6) *p < 0.001
  1. ¥9 patients refused testing or had unknown HIV status, and 4 HIV-infected patients had no CD4 cell count data.
  2. *P values indicate significant differences between patient groups.
  3. §Multiple invalid results.
  4. IQR, Inter-quartile range; SD, Standard deviation; ARV, Anti-retroviral therapy; NYHA, New York Heart Association; ADA, Adenosine deaminase; WCC, White cell count; PF, pericardial fluid.