Figure 6 : Effects of vitamin D on T-cell functions in TNBS- or oxazolone-treated mice.

From: Vitamin D treatment attenuates 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis but not oxazolone-induced colitis

Figure 6

(A) Western blot analyses of the colonic mucosal levels of a Th1 transcription factor (T-bet), a Th2 transcription factor (GATA3) and a Treg cell mediator (Foxp3) in different treatment groups on day 2. (B) In TNBS-treated mice, vitamin D intervention suppresses all Th-1 mediated colonic inflammatory cytokines. **P < 0.01, ***P < 0.001 versus vehicle treatment (n = 6 in each group). (C) Vitamin D treatment slightly aggravates Th-2-mediated inflammatory cytokines induced by oxazolone and increases Treg-related cytokines. *P < 0.05, **P < 0.01 versus vehicle treatment (n = 6 in each group). All electrophoresis was performed under the same condition, and gel images were cropped for concise presentation. The uncut images are provided in Supplementary Materials.