Figure 7 : Akt-mTOR pathway is down-regulated in the endometrium of both ovariectomized rat uterus and postmenopausal females.

From: Menopause-induced uterine epithelium atrophy results from arachidonic acid/prostaglandin E2 axis inhibition-mediated autophagic cell death

Figure 7

(a) Effect of ovariectomy on p-Akt, p-mTOR, p-S6K and p-4EBP1 immunostaining (green) in rat endometrial epithelium. (b) Expression patterns of LC-3, COX-2, EP-4, p-Akt, p-mTOR, and p-S6K in premenopausal endometrium at either proliferative phase or secretory phase and in postmenopausal endometrium at indicated time points.