Figure 1: Sandwich approach for the detection of CRE. | Scientific Reports

Figure 1: Sandwich approach for the detection of CRE.

From: Real time and label free profiling of clinically relevant exosomes

Figure 1

(A) Schematic representation of the sandwich approach for the detection of exosomes in functionalized SPR chip. The chip was first functionalized with biotinylated anti-CD9 or CD63 (Orange) using biotin-avidin chemistry. The exosomes were passed through the SPR machine and captured by the functionalized anti-CD9 and/or anti-CD63 in the SPR chip. The HER2 specific exosomes (Brown) were detected by using anti-HER2 (Violet) (B) Cryo-TEM image of the BT474 cell derived exosomes.

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