Figure 4 | Scientific Reports

Figure 4

From: Acute effects of ferumoxytol on regulation of renal hemodynamics and oxygenation

Figure 4

Ferumoxytol blunts ABP increase during a hyperoxic challenge.

Relative changes in arterial blood pressure, renal blood flow, cortical and medullary tissue perfusion (Flux) and cortical and medullary tissue oxygen tension (pO2) upon a hyperoxic challenge (inspiratory oxygen 100%) at cumulative ferumoxytol doses of 0 (Control), 6, 10 and 41 mg Fe/kg body mass (6 FO, 10 FO, 41 FO). Data at time 380 sec indicate that all variables had returned to baseline values at the end of the respective recovery period (200 sec of normoxia). Data are mean ± SEM; *denotes significant difference (ANOVA for repeated measurements followed by Bonferroni’s multiple comparison procedure).

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