Composition of the colon microbiome in ompK36-immunized and mock-immunized mice.
(A) Area chart of ompK36 immunized and control mice. (B) Bar chart of the average group composition (n = 7/group). (C) Bacterial clade was significantly (P < 0.05) influenced by ompK36 immunization compared to paired controls in ApoE−/− and WT mice. Data are plotted as mean ± s.e.m. Statistical analysis: (one-way ANOVA with Bonferroni’s post hoc test and) student t test. (D) Heatmap graph of correlation analysis between bacterial OTUs and animal traits. Only statistically significant correlations are reported (r factor is shown). Analysis of all mice (n = 28) was performed by QIIME software.