Table 4: TAS2R38 variants and diplotypes and the association with gastric cancer risk.

From: Genetic Variation in the TAS2R38 Bitter Taste Receptor and Gastric Cancer Risk in Koreans

 Model 1 OR (95% CI)*PModel 2 OR (95% CI)P
A49P
 PP1.000 (reference) 1.000 (reference) 
 PA1.392 (1.089–1.780)0.0051.515 (1.149–1.996)0.001
 AA1.025 (0.733–1.435)0.3610.983 (0.676–1.429)0.190
V262A
 AA1.000 (reference) 1.000 (reference) 
 AV1.404 (1.098–1.794)0.0031.525 (1.157–2.009)0.001
 VV0.995 (0.709–1.396)0.2610.957 (0.656–1.395)0.140
I296V
 VV1.000 (reference) 1.000 (reference) 
 VI1.404 (1.098–1.794)0.0031.525 (1.157–2.009)0.001
 II0.995 (0.709–1.396)0.2610.957 (0.656–1.395)0.140
Diplotype
 PAV/PAV1.000 (reference) 1.000 (reference) 
 PAV/AVI1.392 (1.089–1.780)0.0041.513 (1.148–1.994)0.001
 AVI/AVI0.995 (0.709–1.396)0.2720.956 (0.656–1.394)0.145
  1. Subjects with AVI/AAV diplotype were excluded from the analyses because of limited numbers (n = 2).
  2. *Model 1: crude OR and 95% CI.
  3. Model 2: ORs computed after adjusting for sex, age, body mass index, smoking and drinking status, regular exercise and Helicobacter pylori infection (please refer to Supplementary Table S2 for the effect of potential confounders). OR = odds ratio; CI = confidence interval.