Thank you for visiting nature.com. You are using a browser version with
limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off
compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site
Subjects with AVI/AAV diplotype were excluded from the analyses because of limited numbers (n = 2).
*Model 1: crude OR and 95% CI.
†Model 2: ORs computed after adjusting for sex, age, body mass index, smoking and drinking status, regular exercise and Helicobacter pylori infection (please refer to Supplementary Table S2 for the effect of potential confounders). OR = odds ratio; CI = confidence interval.