Figure 1 | Scientific Reports

Figure 1

From: Autoimmune Responses to Soluble Aggregates of Amyloidogenic Proteins Involved in Neurodegenerative Diseases: Overlapping Aggregation Prone and Autoimmunogenic regions

Figure 1

Box and Whisker plots showing average aggregation propensities of the peptide sequences in experimentally validated human T-cell autoimmune epitopes and MHCIInonbind datasets, predicted by (a) TANGO (PAgg-TANGO) and (b) WALTZ (PAgg-WALTZ). All epitope classes (HLA-DP, HLA-DQ and HLA-DR) show long tails suggesting that a number of epitopes in these datasets are aggregation prone.

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