Figure 2 : Astrocytosis increases in response to a western diet in B6 mice.

From: Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

Figure 2

(A,B) Immunofluorescent staining of glial fibrillary acidic protein (GFAP, green) in the hippocampus (HP) increases in B6 mice fed the western diet (B) compared to control diet (A). (C) The number of GFAP+ cells increase in the hippocampus of western diet-fed mice compared to control diet (p < 0.0001, n = 7). (D,E) Immunofluorescent staining of GFAP in the entorhinal cortex (Ctx) increases in B6 mice fed a western diet (E) compared to control diet (D). (F) GFAP+ cell number increases in the entorhinal cortex of B6 mice fed the western diet compared to control diet (p = 0.0002, n = 7). Blue  =  DAPI. Scale bars: 160 μm.