Table 1 Modifiers of PR25-mediated eye degeneration uncovered in a targeted RNAi screen.

From: Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

Fly gene E/S Human gene
Nuclear Pore Complex
 Mtor E TPR
 Nup44A E SEH1
 Nup50 S NUP50
 Nup62 E NUP62
 Nup93-1 E NUP93
 Nup107 S NUP107
 Nup154 S NUP155
Importins/Exportins
 CG32165 S IPO4
 Fs(2)Ket E KPNB1
 Kap-alpha3* E KPNA3, KPNA4
 Ranbp11* E IPO11
 Trn* E TNPO1
 emb E XPO1
Ran-GTP regulators
 RanGap E RANGAP1
 Rcc1* E RCC1
Arginine methytransferases
 Art1 E PRMT1
 Art6 E
 Art7 E PRMT7
 Fbx011 E FBX010, FBX011
  1. *Indicates genes which were independently discovered in genome-wide yeast screens11. S = suppressor; E = enhancer.