Figure 2 | Scientific Reports

Figure 2

From: The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin

Figure 2

Kinetic analysis reveals a high affinity uptake for DNR into the TOV2223G cells.

Uptake rates were recorded for 2.5 min and quantified with the Fluoroskan Ascent microplate reader. The data were fitted to the following equation y = Vmax * x/(Km + x) by means of nonlinear regression using GraphPad Prism (GraphPad Software Inc, CA, USA) to determine Michaelis-Menten constant and maximum velocity. Results are representative of two separate experiments with standard errors.

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