Figure 4 | Scientific Reports

Figure 4

From: Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

Figure 4

Unsupervised analysis (a) and supervised analysis (b) of the combined data obtained with different resting and activated T cell subsets of 3 normal donors co-incubated with TEX or DEX. The data are mean Ct values calculated for mRNA expression levels of each of the 24 genes examined. In (a) note higher Ct values (i.e., lower mRNA expression levels) for a number of immunoregulatory genes in activated T cell subsets. The asterisks indicate differences in gene expression of activated Treg co-incubated with TEX or DEX. In (b) the same data for resting and activated T cell subsets are compared in a supervised analysis to indicate mean Ct values for genes regulating inhibitory, stimulatory, apoptotic or adenosine-related pathways.

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