Figure 8 | Scientific Reports

Figure 8

From: Identification of two novel Chlorotoxin derivatives CA4 and CTX-23 with chemotherapeutic and anti-angiogenic potential

Figure 8

CTX and CA4 inhibit tumor-induced angiogenesis.

Tumor-implanted brain slices were treated with CTX or CA4 for 5 days and tumor vessels were monitored. Control brain sections without tumor implantation and tumor-implanted brain sections without treatment served as controls. Scorpion toxin peptide treatment with CTX and its derivate CA4 reduced vessel density in the peritumor area. Scale bar represents 200 μm.

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