Figure 3 | Scientific Reports

Figure 3

From: Integrated network model provides new insights into castration-resistant prostate cancer

Figure 3

Control effects of the genes in the constructed CRPC regulatory network.

“Controlling Genes” are labeled vertically; “Controlled Genes” are labeled horizontally. Each color scale is assigned a number for easy recognition. The effects on the Controlled Genes through the perturbation of each Controlling Gene are indicated by the corresponding row. The meanings of the colors of the matrix entries (ith row and jth column) are: Dark green box = 3, means node j is co-expressed with node i; Green box = 2, means when node i is “0”, node j is not a constant and node i is “1” results in node j being “1”; Light green box = 1, means node i is “0” results in node j being “0” and when node i is “1”, node j is not a constant; Dark red box = −3, means node j is co-expressed oppositely with node j; Red box = −2, means when node i is “0”, node j is not a constant and node i is “1” results in j being “0”; Light red box = −1, means node i is “0” results in node j being “1” and when node i is “1”, node j is not a constant; Yellow box = 5, means that the regulation is not clear. The white boxes indicate that the controlling genes have no effect on the corresponding column genes.

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