Figure 3 : Plaque detection in apoE−/− mouse model.

From: Targeted gold-coated iron oxide nanoparticles for CD163 detection in atherosclerosis by MRI

Figure 3

(A) Representative magnetic resonance images obtain before (0 h) and after (24 h, 48 h) the injection of each type of nanoparticles. The white arrows point at slightly darker areas with respect to the pre-injection images in the case of apoE−/− mice injected with NP-CD163(m). (B) Graph showing the normalized mean value of the abdominal aortic wall for apoE−/− and wild type mice injected with either NP-CD163(m) or NP-IgG(m) at 0, 24 and 48 hours. The error bars represent the SEM. *p < 0.05, **p < 0.01 and ***p < 0.001 versus apoE + NP-CD163 t = 48h.