Table 3: Risk estimates for lung cancer associated with BMI in stratified analysis.

From: Body mass index and risk of lung cancer: Systematic review and dose-response meta-analysis

Studies groupsNo. of studiesBMI (kg/m2)PI2 (95%CI)
22.525.027.53035
All studies261.00(0.99–1.00)0.98(0.95–1.01)0.95(0.90–1.00)0.91(0.85–0.98)0.81(0.72–0.91)0.0005(0–28)
Sex
 Male151.00(1.00–1.00)0.98(0.98–0.99)0.96(0.95–0.96)0.92(0.91–0.93)0.83(0.80–0.86)0.00014(0–42)
 Female91.00(1.00–1.00)0.98(0.98–0.99)0.97(0.96–0.97)0.94(0.93–0.96)0.88(0.84–0.93)0.04228(0–56)
Smoking status
Current smokers110.99(0.99–0.99)0.97(0.97–0.97)0.95(0.94–0.95)0.92(0.91–0.94)0.87(0.83–0.91)0.46835(0–65)
 Male50.99(0.99–0.99)0.97(0.97–0.98)0.95(0.95–0.96)0.93(0.92–0.95)0.88(0.82–0.96)0.9210(0–60)
 Female61.00(1.00–1.00)0.98(0.98–0.99)0.96(0.95–0.97)0.92(0.89–0.94)0.81(0.75–0.87)0.0000(0–46)
Ex-smokers81.00(0.99–1.00)0.98(0.98–0.99)0.97(0.96–0.98)0.95(0.93–0.97)0.89(0.84–0.94)0.07638(6–59)
 Male51.00(1.00–1.00)0.99(0.98–1.00)0.97(0.96–0.99)0.95(0.92–0.98)0.89(0.82–0.97)0.19840(0–68)
 Female51.00(0.99–1.00)0.98(0.97–1.00)0.97(0.95–0.98)0.94(0.91–0.97)0.88(0.81–0.96)0.23043(1–67)
Non-smokers121.00(1.00–1.00)0.98(0.97–0.99)0.97(0.94–0.99)0.96(0.91–1.01)0.94(0.81–1.08)0.81527(0–50)
 Male71.00(1.00–1.00)0.98(0.97–1.00)0.97(0.93–1.01)0.96(0.86–1.07)0.95(0.71–1.27)0.83037(0–66)
 Female61.00(1.00–1.00)0.98(0.96–1.01)0.97(0.94–1.00)0.95(0.89–1.02)0.92(0.76–1.10)0.85023(0–56)
Histologic type
 Adenocarcinoma51.00(1.00–1.00)0.99(0.98–0.99)0.96(0.95–0.98)0.92(0.90–0.95)0.82(0.76–89)0.00110(0–46)
 Small cell carcinoma31.00(1.00–1.00)0.99(0.98–1.01)0.99(0.97–1.01)0.99(0.97–1.02)1.00(0.92–1.08)0.7740(0–57)
 Squamous cell carcinoma41.00(0.99–1.00)0.98(0.97–0.99)0.97(0.95–0.99)0.96(0.90–0.99)0.90(0.80–1.01)0.62927(0–60)
  1. Note:
  2. The association between BMI and lung cancer risk was evaluated by relative risk (RR) and 95% confidence interval (CI). Besides, normal weight (BMI = 18.5–24.9 kg/m2) was regarded as a reference category.
  3. P value for non-linearity.