Figure 2 : AZ1 binding to ODC monomer.

From: Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1

Figure 2

(a) Residues involved in hydrogen bonds (black dash), ionic (pink dash) and hydrophobic interactions between ODC (purple) and AZ1 (pink) at interface I are shown as sticks. (b) Residues involved in the interactions between ODC C-domain (green) and AZ1 (pink) at interface II are shown as sticks. Color scheme is as before. (c) AZ1 (magenta) occupies the position of the C-terminal domain of the second ODC monomer (beige transparent surface) of the catalytically active homodimer.