Figure 5 | Scientific Reports

Figure 5

From: Epitopes in α8β1 and other RGD-binding integrins delineate classes of integrin-blocking antibodies and major binding loops in α subunits

Figure 5

Epitopes recognised by non-blocking mAbs.

FACS-analyses with α8 non-blocking mAbs, F40, 747 and 753 for wild type and mutant α8 in which the β-propeller domain is replaced with that of αv subunit (αv/α8). L230 and YZ3 recognise the β-propeller domain of αv and α8, respectively and were used to demonstrate the expression of αv/α8.

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