A large sub-network was found to display a negative association between FC and aging using primary thresholds of p < 0.01 and p < 0.005 but not with a primary threshold of p < 0.001 (a). Younger subjects presented moderate positive mean FC values in this network while older subjects presented mean FC values close to zero along the network (b). In the upper panel (a), black dots represent AAL brain regions and blue edges denote edges with negative associations with age. Bottom panel (b) presents scatter plots of the mean FC of the statistically significant networks in function of age.