The active regions in PD compared with control mice quantified by qAIM-MRI.
Regions with significant shortening of T1 in PD mice are indicated by pseudo-colored regions over the T2-enhanced brain image template in sagittal (upper) and coronal (lower) planes (ncontrol = 6 mice, nPD = 6 mice). Regions were defined by brain atlas alignment to MRI image: those regions defined in text, plus nucleus accumbens (NAc), globus pallidus (GP) and hippocampus (HIP). The large colored regions were observed in CPu, Ctx and Th. T: t-value.