Figure 5 : C. albicans internalization is followed by fungal outgrowth.

From: Opportunistic pathogen Candida albicans elicits a temporal response in primary human mast cells

Figure 5

Shown are images of the indicated time points for C. albicans infected mast cells (MOI 0.1). (A) Arrows show an intracellular yeast cell (GFP-expressing C. albicans strain CAI4 pENO1-GFP-CyC1t) replicating inside the mast cell (orange, membrane stain DiI) finally rupturing the plasma membrane as determined by loss of signal. An extracellular C. albicans hyphal tip growing towards a mast cell nudged the host cell and induced collapse of the plasma membrane (*). Complete movies are available as Movie S2 and S3 in the supplemental material. Scale bar, 10 μm.