Figure 6 | Scientific Reports

Figure 6

From: Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for effective monitoring and promoting breast tumor regression

Figure 6

(A) Scanning electron microscopic images of MCF-7 cells treated with control, HZnO (equivalent to weight of the PAC nanoformulation), PAC (IC50) and FCPZnO (IC50) for 48 h. In control cells, healthy filopodia and lamellipodia of MCF-7 cells are observed while truncated cytoplasmic extensions (lamellipodia and filopodia) in PAC and FCPZnO are visualized. (B) Nuclear morphological analysis of Control, HZnO, PAC and FCPZnO treated MCF-7 and MDA-MB-231 cells by DAPI staining (epi-fluorescence microscopic image at 20x and scale bars: 10 μm). Results are representative of three independent experiments.

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