Figure 2 : Time course of fibrillation on surface.

From: Ultrafast propagation of β-amyloid fibrils in oligomeric cloud

Figure 2

(a–g) TIRFM images at several stages of the 10-μM-Aβ1–40 solution-flow measurement indicated by black inverted triangles in Fig. 1a. No fibrillation occurs until ~5000 s despite significant progress of peptide deposition. Dense fibril networks are, however, quickly formed in the later stage. The scale bars indicate 10 μm. (h) An AFM image on the quartz surface after the deposition measurement, showing fibrils embedded in the oligomeric clouds indicated by black arrows. The scale bar indicates 1 μm.