Table 2 Genotype and minor allele frequencies of 9 SNPs in 6 genes in controls, DSPT and FRT individuals

From: Screening of Clock Gene Polymorphisms Demonstrates Association of a PER3 Polymorphism with Morningness–Eveningness Preference and Circadian Rhythm Sleep Disorder

     Control (N = 925) DSPT (N = 182) FRT (N = 67) Control DSPT   FRT  
Gene SNP Allele (A/a) Variation (amino acid) AA Aa aa AA Aa aa AA Aa aa MAF MAF permutated P (χ2) MAF permutated P (χ2)
CLOCK rs1801260 T/C   0.707 0.268 0.025 0.665 0.297 0.038 0.687 0.284 0.03 0.159 0.187 0.218 0.172 0.715
NPAS2 rs2305160 G/A A/T 0.659 0.297 0.043 0.698 0.264 0.038 0.612 0.343 0.045 0.192 0.17 0.355 0.216 0.502
PER1 rs2585405 C/G P/A 0.345 0.477 0.178 0.335 0.538 0.126 0.403 0.418 0.179 0.417 0.396 0.489 0.388 0.535
PER2 rs2304672 C/G   0.893 0.106 0.001 0.918 0.077 0.005 0.866 0.119 0.015 0.054 0.044 0.666 0.075 0.539
  rs934945 G/A G/E 0.476 0.428 0.096 0.516 0.401 0.082 0.448 0.507 0.045 0.31 0.283 0.518 0.299 0.950
PER3 rs228697 C/G P/A 0.846 0.149 0.004 0.846 0.143 0.011 0.716 0.284 0 0.079 0.082 0.941 0.142 0.017*
  rs2640909 T/C M/T 0.782 0.204 0.014 0.775 0.198 0.027 0.657 0.343 0 0.116 0.126 0.765 0.172 0.088
TIM rs774047 A/G Q/R 0.354 0.456 0.19 0.407 0.467 0.126 0.284 0.522 0.194 0.418 0.36 0.058 0.455 0.527
  rs2291739 C/T P/L 0.316 0.474 0.211 0.363 0.489 0.148 0.313 0.478 0.209 0.448 0.393 0.082 0.448 1
  1. A, major allele; a, minor allele; N, number; MAF, minor allele frequency; P, P value for the difference in MAF between DSPT or FRT patients and controls;
  2. *, P < 0.05.