Figure 1 | Scientific Reports

Figure 1

From: Nanoscale Label-free Bioprobes to Detect Intracellular Proteins in Single Living Cells

Figure 1

Gold nanorod Fiber tip probe (FTP).

(a), Scanning Electron Microscope (SEM) image of a FTP. The optical fiber is gradually tapered from 125 um to sub-100 nm. (b), Enlarged SEM image of the end of a FTP showing a single nanorod immobilized on the FTP. (c), Optical image of the LSPR FTP with excitation light source off (left) and on (right) in air. A red dot (right) corresponds to the LSPR of a gold nanorod. In this experiment, white-light from Halogen source was coupled into the fiber and used to excite the gold nanorod at the fiber tip. (d), Image from the spectrometer CCD at the zeroth order grating (left) and a LSPR spectrum at the first order grating (right). This FTP was immersed in 10 mM phosphate buffered saline (PBS).

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