Table 1 Screening of compounds with autophagic activities

From: Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

Categories Compounds name Mean IC50 (HeLa) Dosage used for EGFP-LC3 puncta detection
Flavonoids (±)-Catechin >100 μM 50 μM
  (-)-Epicatechin >100 μM 50 μM
Ginsenosides 20(S)-protopanaxatriol >100 μM 50 μM
  20(S)-protopanaxadiol 22.7 μM 25 μM
Naphthoquinone Shikonin 2.82 μM 5 μM
Alkaloids Magnoflorine >100 μM 50 μM
  Peimine A >100 μM 50 μM
  Peiminine B >100 μM 50 μM
  Rutaecarpine 0.3 μM 5 μM
  Gramine 40.2 μM 50 μM
  Oxymatrine >100 μM 50 μM
  Liensinine 32.4 μM 20 μM
  Isoliensinine 15.8 μM 10 μM
  Dauricine 14.5 μM 10 μM
  Cepharanthine 8.9 μM 10 μM