Table 1: Screening of compounds with autophagic activities

From: Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

CategoriesCompounds nameMean IC50 (HeLa)Dosage used for EGFP-LC3 puncta detection
Flavonoids(±)-Catechin>100 μM50 μM
 (-)-Epicatechin>100 μM50 μM
Ginsenosides20(S)-protopanaxatriol>100 μM50 μM
 20(S)-protopanaxadiol22.7 μM25 μM
NaphthoquinoneShikonin2.82 μM5 μM
AlkaloidsMagnoflorine>100 μM50 μM
 Peimine A>100 μM50 μM
 Peiminine B>100 μM50 μM
 Rutaecarpine0.3 μM5 μM
 Gramine40.2 μM50 μM
 Oxymatrine>100 μM50 μM
 Liensinine32.4 μM20 μM
 Isoliensinine15.8 μM10 μM
 Dauricine14.5 μM10 μM
 Cepharanthine8.9 μM10 μM