Figure 5 : Influence of disruption of kefB on the growth of M. tuberculosis in guinea pigs.

From: KefB inhibits phagosomal acidification but its role is unrelated to M. tuberculosis survival in host

Figure 5

The figure depicts bacillary load in the lungs and spleen of guinea pigs infected with 10–30 bacilli of M. tuberculosis, MtbΔkefB or MtbΔkefBComp at 5 weeks (A) and 10 weeks post-infection (B). Guinea pigs infected with either of the M. tuberculosis strains exhibited a comparable bacillary load in the lungs as well as in the spleen. Each data point represents the log10CFU value for an individual animal and bar depicts mean (±SE) for each group.