Figure 1 : Sustained production of ROS is specific to regeneration.

From: Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed

Figure 1

(a–e) ROS were detected with a fluorescent probe (H2DCFDA) in the time course of regeneration (a–d) or during wounding (e). (a) Top row: merge; bottom row: ROS detection. (b) At 16 hpa and higher magnification, orthogonal projection showed that ROS were primarily detected in the epidermis. (c–d) At 16 hpa, ROS were abundant in the wounded epidermis (c) and decorated adjacent epidermal cells (d). (e) Left panel: ROS detection; right panel: merge. (f) Quantification of the amount of ROS during healing and regeneration. Error bars represent the SEM (**p< 0.01, ***p < 0.001). Scale bars = 20 μm.