Table 1 Significant deregulation of Biocarta pathways in asynchronous Cdc14-null MEFs

From: Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription

Biocarta pathways Adjusted pvalue (FDR) Genes
Alk Pathway 0.016 Gsk3B, Tcf1, Bmp7, Atf2, Apc, Tgfbr1, Bmp10, Nkx2-5, Chrd, Tgfb1, Gata4, Acvr1, Mef2C, Dvl1, Axin1, Bmpr2, Tgfbr2, Fzd1, Bmpr1a, Tgfbr3, Bmp5, Wnt1, Rfc1, Map3K7, Bmp2, Nppb, Tgfb2, Nppa, Nog, Tgfb3, Bmp4.
G1 pathway 0.071 Gsk3B, Tp53, Cdkn1B, E2F1, Atm, Ccna1, Cdk4, Atr, Cdk6, Dhfr, Tgfb1, Abl1, Cdk2, Tfdp1, Rb1, Cdc25a, Skp2, Ccne1, Hdac1, Tgfb2, Cdkn1a, Cdkn2B, Cdkn2a, Tgfb3, Ccnd1.
Cell Cycle 0.135 Cdkn1B, Rbl1, Ccnb1, Ccnh, E2F1, Ccna1, Cdk4, Cdkn2D, Cdk6, Cdk2, Tfdp1, Cdkn2C, Rb1, Cdc25a, Ccne1, Cdk7, Cdkn1a, Ccnd3, Ccnd2, Cdkn2B, Cdkn2a, Ccnd1.