Table 1 Expression of voltage-gated ion channels

From: Transcriptomic analyses of murine ventricular cardiomyocytes

Gene Protein TPM
Sodium channels, voltage-gated
 Scn5a Nav1.5 86.900
 Scn4a Nav1.4 12.163
 Scn7a Nav2.1 1.650
 Scn10a Nav1.8 0.180
 Scn3a Nav1.3 0.123
 Scn2a Nav1.2 0.025
 Scn11a Nav1.9 0.009
 Scn8a Nav1.6 0.004
 Scn1a Nav1.1 0.003
 Scn9a Nav1.7 0.000
 Scn4b β4 subunit 17.765
 Scn1b β1 subunit 6.524
 Scn3b β3 subunit 0.074
 Scn2b β2 subunit 0.041
Calcium channels voltage-gated
 Cacna1c Cav1.2 32.050
 Cacna1s Cav1.1 3.045
 Cacna1g Cav3.1 3.006
 Cacna1h Cav3.2 1.738
 Cacna1a Cav2.1 0.360
 Cacna1d Cav1.3 0.225
 Cacna1b Cav2.2 0.028
 Cacna1i Cav3.3 0.008
 Cacna1e Cav2.3 0.003
 Cacna1f Cav1.4 0.000
 Cacna2d1 α2 and δ1 subunit 30.799
 Cacna2d3 α2 and δ3 subunit 0.048
 Cacna2d4 α2 and δ4 subunit 0.000
 Cacnb2 β2 subunit 8.023
 Cacnb1 β1 subunit 1.714
 Cacnb3 β3 subunit 0.398
 Cacnb4 β4 subunit 0.108
 Cacng6 γ6 subunit 1.513
 Cacna2d2 γ1 subunit 0.455
 Cacng7 γ7 subunit 0.261
 Cacng1 γ7 subunit 0.024
 Cacng4 γ4 subunit 0.010
 Cacng5 γ5 subunit 0.008
 Cacng2 γ2 subunit 0.002
 Cacng3 γ3 subunit 0.000
 Cacng8 γ8 subunit 0.000
Transient receptor potential cation channels
 Trpm7 TRPM7 5.530
 Pkd1 TRPP1 5.248
 Pkd2l2 TRPP5 4.380
 Mcoln1 TRPML1 2.836
 Trpm4 TRPM4 2.431
 Pkd2 TRPP2 2.424
 Trpc1 TRPC1 1.836
 Trpc3 TRPC3 0.875
 Trpv2 TRPV2 0.391
 Trpv4 TRPV4 0.366
 Trpm3 TRPM3 0.287
 Trpc6 TRPC6 0.051
 Trpm6 TRPM6 0.037
 Trpc4 TRPC4 0.033
 Trpv1 TRPV1 0.026
 Trpa1 TRPA1 0.022
 Mcoln3 TRPML3 0.018
 Trpv3 TRPV3 0.016
 Mcoln2 TRPML2 0.011
 Trpm2 TRPM2 0.011
 Trpm5 TRPM5 0.005
 Trpv5 TRPV5 0.005
 Trpv6 TRPV6 0.005
 Trpc7 TRPC7 0.002
 Pkd2l1 TRPP3 0.000
 Trpc2 TRPC2 0.000
 Trpc5 TRPC5 0.000
 Trpm1 TRPM1 0.000
 Trpm8 TRPM8 0.000
CatSper channels
 Catsper2 CATSPER2 1.744
 Catsper3 CATSPER3, CACRC 0.127
 Catsper4 CATSPER4 0.060
 Catsperd δ subunit 0.058
 Catsperg1 γ1 subunit 0.031
 Catsperb β subunit 0.003
 Catsper1 CATSPER1 0.000
 Catsperg2 γ2 subunit 0.000
Two-pore channels
 Tpcn1 TPCN1 4.183
 Tpcn2 TPCN2 0.446
Cyclic nucleotide-regulated channels
 Hcn2 HCN2 9.736
 Hcn4 HCN4 3.661
 Cnga3 CNGA3 1.880
 Cngb3 CNGB3 1.051
 Hcn1 HCN1 0.229
 Cngb1 CNGB1 0.067
 Hcn3 HCN3 0.056
 Cnga1 CNGA1 0.000
 Cnga2 CNGA2 0.000
 Cnga4 CNGA4 0.000
Potassium channels, calcium-activated
 Kcnn1 KCa2.1 5.677
 Kcnn2 KCa2.2 3.107
 Kcnt2 Kna 0.287
 Kcnmb1 β1 subunit 0.127
 Kcnn3 KCa2.3 0.043
 Kcnt1 KCa4.1 0.019
 Kcnu1 KCa5.1 0.014
 Kcnn4 KCa3.1 0.008
 Kcnma1 KCa1.1 0.007
 Kcnmb2 β2 subunit 0.000
 Kcnmb3 β3 subunit 0.000
 Kcnmb4 β4 subunit 0.000
Potassium channels, voltage-gated
 Kcng2 Kv6.2 44.470
 Kcnh2 Kv11.1 17.558
 Kcnd2 Kv4.2 12.960
 Kcnq1 Kv7.1 12.079
 Kcnb1 Kv2.1 8.310
 Kcna5 Kv1.5 4.250
 Kcnv2 Kv8.2 3.502
 Kcnd3 Kv4.3 3.270
 Kcna7 Kv1.7 2.800
 Kcne1 KCNE1 1.917
 Kcnq4 Kv7.4 1.326
 Kcna4 Kv1.4 0.907
 Kcne4 KCNE4 0.833
 Kcnf1 Kv5.1 0.000
 Kcnc3 Kv3.3 0.566
 Kcnc1 Kv3.1 0.237
 Kcna1 Kv1.1 0.175
 Kcne2 KCNE2 0.005
 Kcna6 Kv1.6 0.119
 Kcnab3 KCAB3 0.113
 Kcna2 Kv1.2 0.105
 Kcnab2 KCAB2 0.088
 Kcnab1 KCAB1 0.056
 Kcns1 Kv9.1 0.051
 Kcnq5 Kv7.5 0.048
 Kcnc4 Kv3.4 0.041
 Kcnd1 Kv4.1 0.031
 Kcnc2 Kv3.2 0.029
 Kcnh1 Kv10.1 0.027
 Kcng4 Kv6.4 0.020
 Kcna3 Kv1.3 0.019
 Kcns3 Kv9.3 0.012
 Kcnh3 Kv12.2 0.008
 Kcnh6 Kv11.2 0.007
 Kcng3 Kv6.3 0.005
 Kcne3 KCNE3 0.060
 Kcnq3 Kv7.3 0.004
 Kcnb2 Kv2.2 0.003
 Kcnq2 Kv7.2 0.002
 Kcnh8 Kv12.1 0.002
 Kcna10 Kv1.8 0.000
 Kcng1 Kv6.1 0.000
 Kcnh4 Kv12.3 0.000
 Kcnh5 Kv10.2 0.000
 Kcnh7 Kv11.3 0.000
 Kcns2 Kv9.2 0.000
 Kcnv1 Kv8.1 0.000
Potassium channels, inwardly rectifying
 Abcc9 SUR2A,SUR2B 85.126
 Kcnj11 Kir6.2 51.960
 Kcnj3 Kir3.1 26.920
 Kcnj5 Kir3.4 24.795
 Kcnj2 Kir2.1 20.573
 Kcnj12 Kir2.2 12.050
 Kcnj8 Kir6.1 8.852
 Abcc8 SUR1 8.225
 Kcnj14 Kir2.4, Kir1.3 0.620
 Kcnj4 Kir2.3 0.322
 Kcnj15 Kir4.2 0.105
 Kcnj9 Kir3.3 0.016
 Kcnj1 Kir1.1 0.003
 Kcnj10 Kir4.1, Kir1.2 0.002
 Kcnj13 Kir7.1, Kir1.4 0.000
 Kcnj16 Kir5.1 0.000
 Kcnj6 Kir3.2 0.000
Potassium channels, two-P
 Kcnk3 K2P3.1, TASK-1 76.710
 Kcnk6 K2P6.1, TWIK-2 0.580
 Kcnk1 K2P1.1, TWIK-1 0.280
 Kcnk5 K2P5.1, TASK-2 0.104
 Kcnk2 K2P2.2, TREK-1 0.078
 zKcnk13 K2P13.1, THIK-1 0.066
 Kcnk7 K2P7.1 0.007
 Kcnk10 K2P10.1, TREK-2 0.006
 Kcnk12 K2P12.1, THIK-2 0.000
 Kcnk15 K2P15.1, TASK-5 0.000
 Kcnk16 K2P16.1, TASLK-1 0.000
 Kcnk18 K2P18.1, TRESK-2 0.000
 Kcnk4 K2P4.1, TRAAK 0.000
 Kcnk9 K2P9.1, TASK-3 0.000
Hydrogen voltage-gated ion channels
 Hvcn1 Hv1 0.138
  1. Voltage-gated ion channel genes, their respective proteins, and transcript per million (TPM) values averaged from five WT samples.