Table 2: Demographics for the cohorts included in each of the four studies.

From: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases

  A. Mayo LOAD GWAS (Data Citation 2: Synapse http://dx.doi.org/10.7303/syn2910256) B. Mayo eGWAS (Data Citation 3: Synapse http://dx.doi.org/10.7303/syn3157225,Data Citation 4: Synapse http://dx.doi.org/10.7303/syn3157249) C. Mayo Pilot RNAseq (Data Citation 5: Synapse http://dx.doi.org/10.7303/syn3157268)
      TCX CER TCX
Variables AD (n=844) CON (1,255) AD (n=202) NON-AD (n=197) AD (n=197) NON-AD (n=177) AD (n=94) PSP (N=92)
Mean Age±s.d. (Range) 74.0±4.8 (60–80) 73.2±4.4 (60–80) 73.6±5.5 (60–80) 71.6±5.6 (60–80) 73.6±5.6 (60–80) 71.7±5.5 (60–80) 74.1±5.7 (60–80) 71.9±5.4 (60–80)
APOE4 positive/negative/null (%APOE4 positive) 549/277/18 (65%) 344/889/22 (27%) 123/79/0 (61%) 49/146/2 (25%) 126/71/0 (64%) 45/130/2 (25%) 58/36/0 (62%) 20/72/0 (22%)
Female (%) 482 (57%) 641 (51%) 108 (53%) 78 (40%) 101 (51%) 63 (36%) 41 (44%) 37 (40%)
Mean RIN±s.d. (Range) NA NA 6.3±0.9 (5–9) 6.9±1.0 (5–9.3) 7.2±1.0 (5–9.4) 7.2±1.0 (5–9) 7.0±0.7 (6.2–9) 7.0±0.9 (5.7–9.3)
  D. Mayo RNAseq (Data Citation 6: Synapse http://dx.doi.org/10.7303/syn3163039,Data Citation 7: Synapse http://dx.doi.org/10.7303/syn5049298)
  TCX CER
Variables AD (n=84) PSP (n=84) Path Aging (n=30) Control (n=80) AD (n=86) PSP (n=84) Path Aging (n=28) Control (n=80)
Mean Age±s.d. (Range) 82.4±7.7 (60–90) 74.0±6.5 (61–89) 85.2±4.3 (76–90) 82.6±8.8 (53–90) 82.5±7.7 (60–90) 74.0±6.5 (61–89) 84.7±4.3 (76–90) 82.5±8.3 (58–90)
APOE4 positive/negative (%APOE4 positive) 43/41 (51%) 13/71 (15%) 10/20 (33%) 10/70 (13%) 43/43 (50%) 13/71 (15%) 9/19 (32%) 11/69 (14%)
Female (%) 48 (57%) 33 (39%) 17 (57%) 39 (49%) 49 (57%) 33 (39%) 16 (57%) 39 (49%)
Mean RIN±s.d. (Range) 8.6±0.5 (7.7–10.0) 8.5±0.5 (7.8–10.0) 7.4±1.0 (5.3–8.9) 7.6±1.0 (5.3–9.7) 8.3±0.8 (5.7–10.0) 8.4±0.9 (5.5–10.0) 7.5±1.0 (5.7–9.0) 7.6±1.0 (5.5–9.7)