Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Osteoporotic vertebral collapse with late neurological complications

Abstract

This paper describes 27 patients who had a spinal fracture and underwent an anterior or a posterior spinal decompression, with or without spinal instrumentation, for late neurological compromise secondary to post-traumatic vertebral collapse associated with osteoporosis. Five males and 22 females were studied, with an average follow-up of 3.7 years. The patients developed delayed neurological compromise due to osteoporotic vertebral collapse 1 month to 1.5 years following insignificant spinal fractures. Abnormal hypermobility at the collapsed spinal level with gradual retropulsion of fracture fragments into the spinal canal appeared to contribute to late paralysis. This pathology is treated surgically either anteriorly or posteriorly, but we recommend transpedicular posterolateral decompression and stabilization with a screw-rod construct because of technical ease and minimum invasion.

References

  1. Arciero R A, Leung K Y K, Pierce J H . Spontaneous unstable burst fracture of the thoracolumbar spine in osteoporosis: a report of two cases. Spine 1989; 14: 114–117.

    CAS  Article  PubMed  Google Scholar 

  2. Hammerberg K W, DeWald R L . Senile burst fracture: a complication of osteoporosis. Orthop Trans 1989; 13: 97.

    Google Scholar 

  3. Kaneda A, Yamaura I, Kamikozuru M . Paraplegia as a complication of corticosteroid therapy: a case report. J Bone Joint Surg Am 1984; 66: 783–785.

    CAS  Article  PubMed  Google Scholar 

  4. Kempinsky W H, Morgan P P, Boniface W R . Osteoporotic kyphosis with paraplegia. Neurology 1958; 8: 181–186.

    CAS  Article  PubMed  Google Scholar 

  5. Hammerberg K W . Kyphosis. In: Bridwell KH, DeWald RL (eds). The Textbook of Spinal Surgery, Vol 2. JB Lippincott: Philadelphia 1991; pp 501–524.

    Google Scholar 

  6. Kaplan P A, Orthon D F, Asleson R J . Osteoporosis with vertebral compression fractures, retropulsed fragments and neurologic compromise. Radiology 1987; 165: 533–535.

    CAS  Article  PubMed  Google Scholar 

  7. Maruo S, Takakuwa F, Nakano K . Paraplegie infolge von Wirbel Kompressionsfrakturen bei seniler Osteoporose. Z Orthop 1987; 125: 320–323.

    CAS  Article  PubMed  Google Scholar 

  8. Salomon C, Chopin D, Benoist M . Spinal cord compression: an exceptional complication of spinal osteoporosis. Spine 1988; 13: 222–224.

    CAS  Article  PubMed  Google Scholar 

  9. Tanaka S et al. Conus medullaris syndrome secondary to an L1 burst fracture in osteoporosis. A case report. Spine 1993; 18: 2131–2134.

    CAS  Article  PubMed  Google Scholar 

  10. Japanese Orthopaedic Association. Criteria on the evaluation of the treatment of cervical spondylotic myelopathy. J Jpn Orthop Assoc (Tokyo) 1975; 49: addenda No. 12.

  11. Denis F . The three column spine and its significance in the classification of the acute thoracolumbar spinal injuries. Spine 1983; 8: 817–832.

    CAS  Article  Google Scholar 

  12. Harada A, Ueda H, Kato R, Makino H . Functional radiography for spinal fractures in osteoporosis. Proc Jpn Spine Res Soc (Tokyo) 1994; 5: 234.

    Google Scholar 

  13. Garfin S R, Mowery C A, Guerra J Jr, Marshall L F . Confirmation of the posterolateral technique to decompress and fuse thoracolumbar spine burst fractures. Spine 1985; 10: 218–223.

    CAS  Article  PubMed  Google Scholar 

  14. Abitbol J J, Marshall L, Chesnut R M . Posterolateral spinal canal decompression for traumatic injuries. In: Garfin SR, Northrup BE (eds). Surgery for Spinal Cord Injuries. Raven Press: New York, 1993, pp 239–244.

    Google Scholar 

  15. McCormick P C . The lateral extracavitary approach to the thoracic and lumbar spine. In: Holtzman RNN, McCormick PC, Farcy JPC (eds). Spinal Instability. Springer-Verlag: New York 1993, pp 335–347.

    Chapter  Google Scholar 

  16. Thevenon A et al. Relationship between kyphosis, scoliosis, and osteoporosis in the elderly population. Spine 1987; 12: 744–745.

    CAS  Article  PubMed  Google Scholar 

  17. Kostuik J P . Compression fractures and surgery in the osteoporotic patient. In: Frymoyer JW et al (eds). The Adult Spine: Principles and Practice, Vol 1. Raven Press: New York, 1991, pp 661–677.

    Google Scholar 

  18. Barlow D H . Estrogen treatment of established osteoporosis. In: Cooper C, Reeve J (eds). Spine: State of the Art Reviews. Vertebral Osteoporosis, Vol 8, Book 1. Hanley & Belfus: Philadelphia 1994, pp 189–197.

    Google Scholar 

  19. Gallagher J C . Antiresorptive therapy in osteoporosis. In: Cooper C, Reeve J (eds). Spine: State of the Art Reviews. Vertebral Osteoporosis, Vol 8, Book 1. Hanley & Belfus: Philadelphia 1994, pp 199–223.

    Google Scholar 

  20. Kaneda K et al. The treatment of osteoporotic posttraumatic vertebral collapse using the Kaneda device and a bioactive ceramic vertebral prosthesis. Spine 1992; 17: S295–S303.

    CAS  Article  PubMed  Google Scholar 

  21. Kaneda K, Abumi K, Fujiya M . Burst fractures with neurologic deficits of the thoracolumbar-lumbar spine: results of anterior decompression and stabilization with anterior instrumentation. Spine 1984; 9: 788–795.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  22. Tomita K et al. Circumspinal decompression for thoracic myelopathy due to combined ossification of the posterior longitudinal ligament and ligamentum flavum. Spine 1990; 15: 1114–1120.

    CAS  Article  Google Scholar 

  23. Shikata J et al. Surgical treatment for paraplegia resulting from vertebral fracture in senile osteoporosis. Spine 1990; 15: 85–89.

    Article  Google Scholar 

  24. DeSmet A A, Robinson R G, Johnson B E, Lukert B P . Spinal compression fractures in osteoporotic women: patterns and relationship to hyperkyphosis. Radiology 1988; 166: 497–580.

    CAS  Article  Google Scholar 

  25. Hodges S D et al. The use of transpedicular fixation in the treatment of thoracolumbar and lumbosacral spine fractures. In: Lorenz M (ed). Spine: State of the Art Reviews. Spinal Fracture-Dislocations, Vol 8, Book 2. Hanley & Belfus: Philadelphia, 1993, pp 287–297.

    Google Scholar 

  26. Krieg J C, Zuber K, Weinstein J N . Pedicle screw fixation in the thoracolumbar spine. In: Garfin SR, Northrup BE (eds). Surgery for Spinal Cord Injuries. Raven Press: New York, 1993, pp 227–237.

    Google Scholar 

  27. Gilbert S G, Johns P C, Chow D C, Black R C . Relation of vertebral bone screw axial pullout strength to quantitative computed tomographic trabecular bone mineral content. J Spinal Disord 1993, 6: 513–521.

    CAS  Article  PubMed  Google Scholar 

  28. Shibata T, Yamamoto H, Kamioka Y, Iso H . Biomechanical study of the self-setting hydroxyapatite cement injection into the vertebra with osteoporosis. J Jpn Spine Res Soc (Tokyo) 1994; 5: 336.

    Google Scholar 

Download references

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Baba, H., Maezawa, Y., Kamitani, K. et al. Osteoporotic vertebral collapse with late neurological complications. Spinal Cord 33, 281–289 (1995). https://doi.org/10.1038/sc.1995.64

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/sc.1995.64

Keywords

  • spinal fracture
  • osteoporosis
  • late paraparesis
  • kyphosis
  • spinal instrumentation

Further reading

Search

Quick links