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A self-driving lab for accelerated catalyst development

A self-driving lab, called Fast-Cat, is developed for the rapid, autonomous Pareto-front mapping of homogeneous catalysts in high-pressure, high-temperature gas–liquid reactions. The efficacy of Fast-Cat was demonstrated in performing Pareto-front mappings of phosphorus-based ligands for the hydroformylation of olefins.

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Fig. 1: Fast-Cat’s experimental setup and closed-loop optimization cycle.


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This is a summary of: Bennett, J. A. et al. Autonomous reaction Pareto-front mapping with a self-driving catalysis laboratory. Nat. Chem. Eng. (2024).

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A self-driving lab for accelerated catalyst development. Nat Chem Eng 1, 206–207 (2024).

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