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An engineering makeover of biomedical research

The clinical translation of research findings into improvements in human health can take decades. Engineers perform biomedical research with a solution-oriented mind-set, generating tools and concepts that enable the transformation of knowledge into medical solutions. In this light, bioengineering becomes the driving force for accelerating clinical translation and introducing new concepts in validation, prevention, diagnostics and precision therapy.

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Fig. 1: Engineering as the driving force toward clinical solutions.


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We acknowledge the advice of T. Schwarz-Romond in developing this article; several EU and German research programs that have funded research to advance bioengineering concepts, including the European Research Council (ERC), the Horizon 2020 program, the German Research Foundation (DFG) and the German Federal Ministry of Education and Research (BMBF); and the support of bioengineering concepts from the presidents of the Technical University of Munich, T. Hofmann and W. Herrmann, and O. Wiestler of the Helmholtz Association.

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Correspondence to Vasilis Ntziachristos or Stephen R. Quake.

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V.N. is a founder and shareholder of the medical technology companies iThera Medical GmbH, sThesis GmbH, I3 Inc. and Spear UG.

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Ntziachristos, V., Quake, S.R. & Tschöp, M. An engineering makeover of biomedical research. Nat Rev Bioeng 1, 154–155 (2023).

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