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Personality traits linked to risk of brain disorder

The role of personality in brain health remains unclear. A systematic search demonstrated that lower levels of warmth, diligence, sociability and curiosity, and a higher level of nervousness, were predictive of increased risk of brain disorders. Brain structure, inflammation and lipid metabolism partially explain the associations between personality and brain disorders.

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Fig. 1: The associations between personality and brain health.


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This is a summary of: Zhang, Y.-R. et al. Personality traits and brain health: a large prospective cohort study. Nat. Ment. Health (2023).

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Personality traits linked to risk of brain disorder. Nat. Mental Health 1, 707–708 (2023).

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