Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Arrhythmia

Epicardial adipose tissue resident memory T cells in atrial fibrillation

A resident memory T cell subpopulation that infiltrates epicardial adipose tissue is expanded in patients with atrial fibrillation and may affect cardiomyocyte physiology.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: EAT-derived TRM cells can influence cardiomyocyte function in the context of AF.

References

  1. Kornej, J. et al. Circ. Res. 127, 4–20 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Yao, C. et al. Circulation 138, 2227–2242 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Hulsmans, M. et al. Science 381, 231–239 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Maguy, A. et al. Circulation 148, 487–498 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Vyas, V. et al. Nat. Cardiovasc. Res. https://doi.org/10.1038/s44161-024-00532-x (2024).

    Article  Google Scholar 

  6. Mazurek, T. et al. Circulation 108, 2460–2466 (2003).

    Article  PubMed  Google Scholar 

  7. McCauley, M. D. et al. J. Am. Coll. Cardiol. 83, 2015–2027 (2024).

    Article  CAS  PubMed  Google Scholar 

  8. Vyas, V. et al. JCI Insight 6, e145495 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Kim, J. A. et al. Curr. Opin. Cardiol. 36, 281–287 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Tzialla, C. et al. Eur. J. Med. Genet. 65, 104639 (2022).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Marinos Kallikourdis.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ruggeri, F., Papadopoulou, V. & Kallikourdis, M. Epicardial adipose tissue resident memory T cells in atrial fibrillation. Nat Cardiovasc Res 3, 1026–1027 (2024). https://doi.org/10.1038/s44161-024-00528-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s44161-024-00528-7

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing